Entity Central Index Key Cover [Abstract] Document Type Document Type Amendment Flag Amendment Flag Document Period End Date Document Period End Date Document Fiscal Year Focus Document Fiscal Year Focus Document Fiscal Period Focus Document Fiscal Period Focus Trading Symbol Trading Symbol Entity Registrant Name Entity Registrant Name Entity Central Index Key Current Fiscal Year End Date Current Fiscal Year End Date Entity Current Reporting Status Entity Current Reporting Status Entity Filer Category Entity Filer Category Entity Small Business Entity Small Business Entity Emerging Growth Company Entity Emerging Growth Company Entity Ex Transition Period Entity Ex Transition Period Entity Shell Company Entity Shell Company Entity File Number Entity File Number Entity Tax Identification Number Entity Tax Identification Number Entity Address, Address Line One Entity Address Address Line1 Entity Address, Address Line Two Entity Address Address Line2 Entity Address, City or Town Entity Address City Or Town Entity Address, State or Province Entity Address State Or Province Entity Address, Postal Zip Code Entity Address Postal Zip Code City Area Code City Area Code Local Phone Number Local Phone Number Entity Common Stock, Shares Outstanding Entity Common Stock Shares Outstanding Title of 12(b) Security Security12b Title Security Exchange Name Security Exchange Name Entity Incorporation, State or Country Code Entity Incorporation State Country Code Entity Interactive Data Current Entity Interactive Data Current Document Quarterly Report Document Quarterly Report Document Transition Report Document Transition Report Build-to-suit lease liability. Statement Of Financial Position [Abstract] ASSETS Assets [Abstract] Current assets: Assets Current [Abstract] Cash and cash equivalents Cash And Cash Equivalents At Carrying Value Prepaid expenses and other current assets Prepaid Expense And Other Assets Current Total current assets Assets Current Restricted cash Restricted Cash Deferred lease asset Deferred Costs Leasing Net Noncurrent Property, plant and equipment, net Property Plant And Equipment Net Other non-current assets Other Assets Noncurrent Total assets Assets LIABILITIES AND STOCKHOLDERS' EQUITY Liabilities And Stockholders Equity [Abstract] Current liabilities Liabilities Current [Abstract] Accounts payable Accounts Payable Current Accrued expenses and other current liabilities Accrued Liabilities And Other Liabilities Total current liabilities Liabilities Current Build-to-suit lease liability Build To Suit Lease Liability Term loan, net Long Term Debt Noncurrent Other non-current liabilities Other Liabilities Noncurrent Total liabilities Liabilities Commitments and contingencies - Note 9 Commitments And Contingencies Stockholders' equity Stockholders Equity [Abstract] Preferred stock, $0.00001 par value per share; 10,000,000 shares authorized and no shares issued and outstanding as of September 30, 2022 and December 31, 2021 Preferred Stock Value Common stock, $0.00001 par value per share; 200,000,000 shares authorized and 41,175,939 and 38,473,945 issued and outstanding as of September 30, 2022 and December 31, 2021, respectively Common Stock Value Additional paid-in capital Additional Paid In Capital Accumulated deficit Retained Earnings Accumulated Deficit Total stockholders’ equity Stockholders Equity Total liabilities and stockholders' equity Liabilities And Stockholders Equity Preferred stock, par value per share Preferred Stock Par Or Stated Value Per Share Preferred stock, shares authorized Preferred Stock Shares Authorized Preferred stock, shares issued Preferred Stock Shares Issued Preferred stock, shares outstanding Preferred Stock Shares Outstanding Common stock, par value per share Common Stock Par Or Stated Value Per Share Common stock, shares authorized Common Stock Shares Authorized Common stock, shares issued Common Stock Shares Issued Common stock, shares outstanding Common Stock Shares Outstanding Income Statement [Abstract] Operating expenses: Operating Expenses [Abstract] Research and development Research And Development Expense General and administrative General And Administrative Expense Total operating expenses Operating Expenses Loss from operations Operating Income Loss Other income (expense): Nonoperating Income Expense [Abstract] Interest income Interest Income Expense Nonoperating Net Interest expense Interest Expense Other expense Other Nonoperating Expense Total other expense, net Nonoperating Income Expense Net loss Net Income Loss Net loss per common share, basic Earnings Per Share Basic Net loss per common share, diluted Earnings Per Share Diluted Weighted average common shares outstanding, basic Weighted Average Number Of Shares Outstanding Basic Weighted average common shares outstanding, diluted Weighted Average Number Of Diluted Shares Outstanding Issuance of common stock upon vesting and settlement of restricted stock unit shares. Statement Of Stockholders Equity [Abstract] Statement [Table] Statement [Table] Equity Components Statement Equity Components [Axis] Equity Component Equity Component [Domain] Common Stock Common Stock [Member] Additional Paid-in Capital Additional Paid In Capital [Member] Accumulated Deficit Retained Earnings [Member] Statement [Line Items] Statement [Line Items] Balance Balance, shares Stock-based compensation Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Issuance of common stock, net of sales commissions and other offering costs Stock Issued During Period Value New Issues Issuance of common stock, net of sales commissions and other offering costs, shares Stock Issued During Period Shares New Issues Issuance of common stock upon vesting and settlement of restricted stock units Issuance Of Common Stock Upon Vesting And Settlement Of Restricted Stock Unit Shares Issuance of common stock under ESPP Stock Issued During Period Value Employee Stock Purchase Plan Issuance of common stock under ESPP, Shares Stock Issued During Period Shares Employee Stock Purchase Plans Net loss Balance Balance, shares Payment of sales commissions and other offering costs. Payment of sales commissions and other offering costs Payment Of Sales Commissions And Other Offering Costs Increase decrease in accrued expense and other liabilities. Proceeds from term loan, net. Payment of shelf registration costs. Property and equipment in accounts payable and accrued expenses. Research and development license not yet paid. Statement Of Cash Flows [Abstract] Cash flows from operating activities Net Cash Provided By Used In Operating Activities [Abstract] Net loss Profit Loss Adjustments to reconcile net loss to net cash used in operating activities: Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Depreciation expense Depreciation Research and development license expense Research And Development In Process Stock-based compensation Share Based Compensation Other Other Noncash Income Expense Changes in operating assets and liabilities: Increase Decrease In Operating Capital [Abstract] Prepaid expenses and other assets Increase Decrease In Prepaid Deferred Expense And Other Assets Accounts payable Increase Decrease In Accounts Payable Accrued expenses and other liabilities Increase Decrease In Accrued Expense And Other Liabilities Due to related party Increase Decrease In Due To Related Parties Net cash used in operating activities Net Cash Provided By Used In Operating Activities Cash flows from investing activities Net Cash Provided By Used In Investing Activities [Abstract] Purchase of research and development license Payments To Acquire In Process Research And Development Purchase of property, plant and equipment Payments To Acquire Property Plant And Equipment Net cash used in investing activities Net Cash Provided By Used In Investing Activities Cash flows from financing activities Net Cash Provided By Used In Financing Activities [Abstract] Proceeds from Term Loan, net Proceeds From Term Loan Net Proceeds from issuance of common stock, net of sales commissions Proceeds From Issuance Of Common Stock Payment of shelf registration costs Payment Of Shelf Registration Costs Proceeds from common stock issuances under ESPP Proceeds From Stock Plans Other Proceeds From Payments For Other Financing Activities Net cash provided by financing activities Net Cash Provided By Used In Financing Activities Net decrease in cash, cash equivalents and restricted cash Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect Cash, cash equivalents and restricted cash at the beginning of the period Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations Cash, cash equivalents and restricted cash at the end of the period Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Cash paid for interest Interest Paid Net Supplemental disclosure of noncash investing and financing activities: Noncash Investing And Financing Items [Abstract] Property, plant and equipment in accounts payable and accrued expenses Property And Equipment In Accounts Payable And Accrued Expenses Acquisition of property, plant and equipment funded by landlord Noncash Or Part Noncash Acquisition Fixed Assets Acquired1 Deferred offering costs not yet paid Capital Expenditures Incurred But Not Yet Paid Purchase of research and development license not yet paid Research And Development License Not Yet Paid Build-to-suit lease liability Capital Lease Obligations Incurred Organization Consolidation And Presentation Of Financial Statements [Abstract] Organization and Description of Business Operations Organization Consolidation And Presentation Of Financial Statements Disclosure [Text Block] Accounting Policies [Abstract] Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Balance Sheet Related Disclosures [Abstract] Balance Sheet Components Supplemental Balance Sheet Disclosures [Text Block] Debt Disclosure [Abstract] Loan with Silicon Valley Bank Debt Disclosure [Text Block] Research, collaboration and license agreements. Research Collaboration And License Agreements [Abstract] Research, Collaboration and License Agreements Collaborative Arrangement Disclosure [Text Block] Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Stock-Based Compensation Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Earnings Per Share [Abstract] Net Loss Per Common Share Earnings Per Share [Text Block] Income Tax Disclosure [Abstract] Income Taxes Income Tax Disclosure [Text Block] Commitments And Contingencies Disclosure [Abstract] Commitments and Contingencies Commitments And Contingencies Disclosure [Text Block] Restructuring And Related Activities [Abstract] Strategic Reprioritization Business Acquisition Integration Restructuring And Other Related Costs [Text Block] Compensation And Retirement Disclosure [Abstract] Retirement Plan Pension And Other Postretirement Benefits Disclosure [Text Block] Subsequent Events [Abstract] Subsequent Events Subsequent Events [Text Block] Basis of Presentation Basis Of Accounting Policy Policy [Text Block] Principles of Consolidation Consolidation Policy [Text Block] Use of Estimates Use Of Estimates Comprehensive Loss Comprehensive Income Policy Policy [Text Block] Recently issued accounting pronouncements policy. Recently Issued Accounting Pronouncements Recently Issued Accounting Pronouncements Policy Policy [Text Block] Schedule of Prepaid Expenses and Other Current Assets Deferred Costs Capitalized Prepaid And Other Assets Disclosure [Text Block] Schedule of Property Plant and Equipment Net Property Plant And Equipment [Text Block] Schedule of accrued expense and other current labilities. Schedule of Accrued Expense and Other Current Labilities Schedule Of Accrued Expense And Other Current Labilities Table [Text Block] Schedule of Future Principal Debt Payments on Loan Payable Schedule Of Maturities Of Long Term Debt Table [Text Block] Award Type Award Type [Axis] Award Type Share Based Compensation Arrangements By Share Based Payment Award Award Type And Plan Name [Domain] Stock Options Employee Stock Option [Member] Schedule of Assumptions Used to Estimate Fair Value of Stock Options and Cancelled Options Schedule Of Share Based Payment Award Stock Options Valuation Assumptions Table [Text Block] Schedule of Stock Option Activity Schedule Of Share Based Compensation Activity Table [Text Block] Schedule of Restricted Stock Units Activity Schedule Of Nonvested Restricted Stock Units Activity Table [Text Block] Schedule of Restricted Stock Awards Activity Nonvested Restricted Stock Shares Activity Table [Text Block] Schedule of Total Stock-Based Compensation Expense for Stock Options, ESPP, RSAs and RSUs Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Schedule of Calculation of Basic and Diluted Net Loss Per Common Share Schedule Of Earnings Per Share Basic And Diluted Table [Text Block] Schedule of Common Stock Equivalents Outstanding Excluded from Computation of Diluted Net Loss Per Share Attributable to Common Stockholders Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Text Block] Organization and description of business operations. Organization and description of business operations. Organization And Description Of Business Operations [Table] Organization And Description Of Business Operations [Table] Collaborative Arrangement and Arrangement Other than Collaborative Type Of Arrangement [Axis] Collaborative Arrangement and Arrangement Other than Collaborative Arrangements And Nonarrangement Transactions [Member] Sales Agreement. Sales Agreement Sales Agreement [Member] Product and Service Product Or Service [Axis] Product and Service Products And Services [Domain] Sales agent. Sales Agents Sales Agent [Member] Statistical Measurement Range [Axis] Statistical Measurement Range [Member] Maximum Maximum [Member] Minimum [Member] Minimum [Member] Sale of Stock Subsidiary Sale Of Stock [Axis] Sale of Stock Sale Of Stock Name Of Transaction [Domain] Private Placement [Member] Private Placement [Member] Securities purchase agreement. Securities Purchase Agreement Securities Purchase Agreement [Member] Underwriting agreement. Underwriting Agreement Underwriting Agreement [Member] Counterparty Name Counterparty Name [Axis] Counterparty Name Repurchase Agreement Counterparty Name [Domain] Astellas. Astellas Astellas [Member] Organization and Description of Business Operations [Line Items] Organization And Description Of Business Operations [Line Items] Date of incorporation Entity Incorporation Date Of Incorporation Aggregate offering price from sale of common stock. Percentage of sale price per share of common stock. Common stock shares issued and sold. Aggregate offering price from sale of common stock Aggregate Offering Price From Sale Of Common Stock Percentage of gross sales price per share of common stock Percentage Of Sale Price Per Share Of Common Stock Common stock shares issued and sold Common Stock Shares Issued And Sold Number of shares issued Net proceeds from issuance of common stock Upfront payment. Proceeds from issuance of common stock including upfront payments. Option to purchase additional number of shares. Underwriter agreed to purchase share price of per share. Proceeds from issuance of common stock if underwriter exercises options. Underwriter period for option to purchase additional share. Upfront payment Upfront Payment Gross proceeds including upfront payments Proceeds From Issuance Of Common Stock Including Upfront Payments Underwriter period for option to purchase additional share Underwriter Period For Option To Purchase Additional Share Option to purchase additional number of shares Option To Purchase Additional Number Of Shares Underwriter agreed to purchase share price of per share Underwriter Agreed To Purchase Share Price Of Per Share Estimated net proceeds from offering if underwriter exercises options Proceeds From Issuance Of Common Stock If Underwriter Exercises Options Prepaid research and development contracts. Prepaid clinical trial. Prepaid bonus. Prepaid research and development Prepaid Research And Development Contracts Prepaid clinical trial Prepaid Clinical Trial Deferred offering costs Deferred Offering Costs Prepaid insurance Prepaid Insurance Prepaid bonus Prepaid Bonus Other Other Assets Current Total prepaid expenses and other current assets Schedule Of Property Plant And Equipment [Table] Schedule Of Property Plant And Equipment [Table] Long-Lived Tangible Asset Property Plant And Equipment By Type [Axis] Long-Lived Tangible Asset Property Plant And Equipment Type [Domain] Leasehold Improvements Leasehold Improvements [Member] Laboratory equipment. Laboratory Equipment Laboratory Equipment [Member] Computer Equipment Computer Equipment [Member] Furniture and Fixtures Furniture And Fixtures [Member] Construction in Progress Construction In Progress [Member] Property Plant And Equipment [Line Items] Property Plant And Equipment [Line Items] Property, plant and equipment, gross Property Plant And Equipment Gross Accumulated depreciation Accumulated Depreciation Depletion And Amortization Property Plant And Equipment Property, plant and equipment, net Build-to-suit lease. Build-to-Suit Lease Build To Suit Lease [Member] Payroll and payroll-related costs. Payroll and Payroll Related Costs Payroll And Payroll Related Costs [Member] Construction in progress Construction In Progress Gross Accrued research and development current. Accrued license fees current. Accrued property, plant, and equipment current. Accrued clinical trial current. Accrued research and development Accrued Research And Development Current Accrued compensation Employee Related Liabilities Current Accrued license fees Accrued License Fees Current Accrued property, plant and equipment Accrued Property Plant And Equipment Current Accrued clinical trial Accrued Clinical Trial Current Accrued professional and consulting fees Accrued Professional Fees Current Other Other Accrued Liabilities Current Total accrued expenses and other current liabilities Number of distinct and active clinical stage. Debt Instrument [Table] Debt Instrument [Table] Debt Instrument Debt Instrument [Axis] Debt Instrument, Name Debt Instrument Name [Domain] Term loan through december thirty one twenty twenty one. Through December 31, 2021 Term Loan Through December Thirty One Twenty Twenty One [Member] Term loan from january one twenty twenty two until september thirty twenty twenty two. January 1, 2022 until September 30, 2022 Term Loan From January One Twenty Twenty Two Until September Thirty Twenty Twenty Two [Member] Term loan from october one twenty twenty two until march thirty one twenty twenty three. October 1, 2022 until March 31, 2023 Term Loan From October One Twenty Twenty Two Until March Thirty One Twenty Twenty Three [Member] Term loan from april one twenty twenty three until december thirty one twenty twenty three. April 1, 2023 until December 31, 2023 Term Loan From April One Twenty Twenty Three Until December Thirty One Twenty Twenty Three [Member] Long-Term Debt, Type Longterm Debt Type [Axis] Long-Term Debt, Type Longterm Debt Type [Domain] Term loan facility. Term Loan Term Loan Facility [Member] Variable Rate Variable Rate [Axis] Variable Rate Variable Rate [Domain] Prime Rate Prime Rate [Member] Term loan through august thirteen twenty twenty three. Through August 13, 2023 Term Loan Through August Thirteen Twenty Twenty Three [Member] Debt Instrument [Line Items] Debt Instrument [Line Items] Maximum borrowing capacity Line Of Credit Facility Maximum Borrowing Capacity Debt instrument, maturity date Debt Instrument Maturity Date Debt instrument, maturity start date Debt Instrument Maturity Date Range Start1 Debt instrument, maturity end date Debt Instrument Maturity Date Range End1 Number of distinct and active clinical stage Number Of Distinct And Active Clinical Stage Current borrowing capacity Line Of Credit Facility Current Borrowing Capacity Percentage of interest rate Debt Instrument Interest Rate Stated Percentage Debt instrument, basis spread on variable rate Debt Instrument Basis Spread On Variable Rate1 Percentage of prepayment premium Percentage of prepayment of facility. Percentage of prepayment premium Percentage Of Prepayment Premium Percentage of prepayment of facility Percentage Of Prepayment Of Facility Warrants associated with loan facility Warrants And Rights Outstanding Exit fee recorded as debt discount Debt Instrument Unamortized Discount Noncurrent Percentage of annual default interest rate. Percentage of annual default interest rate Percentage Of Annual Default Interest Rate Interest expense related to term loan Interest Expense Long Term Debt 2022 Long Term Debt Maturities Repayments Of Principal Remainder Of Fiscal Year 2023 Long Term Debt Maturities Repayments Of Principal In Next Twelve Months 2024 Long Term Debt Maturities Repayments Of Principal In Year Two 2025 Long Term Debt Maturities Repayments Of Principal In Year Three 2026 Long Term Debt Maturities Repayments Of Principal In Year Four Total principal payments Debt Instrument Carrying Amount Unamortized debt discount Debt Instrument Unamortized Discount Term Loan, net Long Term Debt Preclinical activities period under sponsored research agreements. Minimum licensed product to develop obtain regulatory approval for and commercialize. Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] UT southwestern agreement. UT Southwestern Agreement U T Southwestern Agreement [Member] Queen's agreement. Queens Agreement Queens Agreement [Member] Income Statement Location Income Statement Location [Axis] Income Statement Location Income Statement Location [Domain] Research and Development Expense Research And Development Expense [Member] Abeona CLN1 agreements. Abeona CLN1 Agreements Abeona C L N1 Agreements [Member] Abeona Rett agreement. Abeona Rett Agreement Abeona Rett Agreement [Member] Abeona Therapeutics Inc. Abeona Abeona Therapeutics Inc [Member] Acquisition of worldwide rights for TSHA 120 for treatment of giant axonal neuropathy. TSHA-120 Acquisition Of Worldwide Rights For T S H A120 For Treatment Of Giant Axonal Neuropathy [Member] License agreement for CLN7. License Agreement for CLN7 License Agreement For C L N7 [Member] Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Preclinical activities period under sponsored research agreements Preclinical Activities Period Under Sponsored Research Agreements Minimum licensed product to develop obtain regulatory approval for and commercialize Minimum Licensed Product To Develop Obtain Regulatory Approval For And Commercialize Percentage of fully diluted common stock shares outstanding. Percentage of common stock shares entitled to receive additional shares on fully diluted basis. Percentage of fully diluted common stock shares outstanding Percentage Of Fully Diluted Common Stock Shares Outstanding Percentage of entitled to receive additional shares on fully diluted basis Percentage Of Common Stock Shares Entitled To Receive Additional Shares On Fully Diluted Basis Payments to acquire license right. License agreement regulatory milestones payment. License agreement commercial milestones payment. Additional Milestone payments. Cash payment to acquire license agreement Payments To Acquire License Right License agreement regulatory milestones payment License Agreement Regulatory Milestones Payment License agreement commercial milestones payment License Agreement Commercial Milestones Payment Additional milestone payments Additional Milestone Payments Payment of license fee. Purchase of clinical materials and reimbursement incurred development costs. License and inventory purchase agreement regulatory related milestones payment. License and inventory purchase agreement sales related milestones payment. License fee payment Payment Of License Fee Purchase of clinical materials and reimbursement incurred development costs Purchase Of Clinical Materials And Reimbursement Incurred Development Costs License and inventory purchase agreement regulatory related milestones payment License And Inventory Purchase Agreement Regulatory Related Milestones Payment License and inventory purchase agreement sales related milestones payment License And Inventory Purchase Agreement Sales Related Milestones Payment Regulatory related milestones obligation payable. Sale-related milestones per licensed product and royalties on net sales of licensed products payable. Payment of one-time upfront license fee. Regulatory milestone fee paid. Payment of one-time upfront license fee Payment Of One Time Upfront License Fee Regulatory related milestones obligation payable Regulatory Related Milestones Obligation Payable Sale-related milestones per licensed product and royalties on net sales of licensed products payable Sale Related Milestones Per Licensed Product And Royalties On Net Sales Of Licensed Products Payable Regulatory milestone fee paid Regulatory Milestone Fee Paid Clinical, regulatory and commercial milestones to be received. Clinical, regulatory and commercial milestones to be received Clinical Regulatory And Commercial Milestones To Be Received License agreement regulatory related milestones maximum amount payable. License agreement sales-related milestones maximum amount payable. License agreement regulatory related milestones maximum amount payable License Agreement Regulatory Related Milestones Maximum Amount Payable License agreement sales-related milestones maximum amount payable License Agreement Sales Related Milestones Maximum Amount Payable Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Plan Name Plan Name [Axis] Plan Name Plan Name [Domain] Two thousand twenty equity incentive plan. 2020 Equity Incentive Plan Two Thousand Twenty Equity Incentive Plan [Member] Two thousand twenty stock incentive plan. New Plan Two Thousand Twenty Stock Incentive Plan [Member] Employee stock purchase plans. Employee Stock Purchase Plan (ESPP) Employee Stock Purchase Plans [Member] Cancelled options. Cancelled Options Cancelled Options [Member] Restricted Stock Units Restricted Stock Units R S U [Member] Title of Individual Title Of Individual [Axis] Title of Individual Title Of Individual With Relationship To Entity [Domain] Certain employees and consultants. Certain Employees and Consultants Certain Employees And Consultants [Member] Vesting Vesting [Axis] Vesting Vesting [Domain] Share-based Payment Arrangement, Tranche One Share Based Compensation Award Tranche One [Member] Share-based Payment Arrangement, Tranche Two Share Based Compensation Award Tranche Two [Member] Share-based Payment Arrangement, Tranche Three Share Based Compensation Award Tranche Three [Member] Share based compensation award tranche four. Share-based Payment Arrangement, Tranche Four Share Based Compensation Award Tranche Four [Member] President and chief executive officer. RA Session II President And Chief Executive Officer [Member] Restricted Stock Awards Restricted Stock [Member] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Number of shares authorized for issuance Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Authorized Share based compensation arrangement by share based payment award commencement date. Percentage of automatic increase every year in common stock shares reserved for future issuance. Common stock reserved for future issuance Common Stock Capital Shares Reserved For Future Issuance Share-based payment award, expiration period Sharebased Compensation Arrangement By Sharebased Payment Award Expiration Period Share-based payment award, commencement date Share Based Compensation Arrangement By Share Based Payment Award Commencement Date Share-based payment award, expiration date Share Based Compensation Arrangement By Share Based Payment Award Expiration Date Percentage of automatic increase every year in common stock shares reserved for future issuance Percentage Of Automatic Increase Every Year In Common Stock Shares Reserved For Future Issuance Share-based payment award, terms of award issuance Share Based Compensation Arrangement By Share Based Payment Award Terms Of Award Number of shares of common stock issued under ESPP Share based compensation arrangement by share based payment award options grants in period grant date fair value. Share based compensation arrangement by share based payment award equity instruments other than options replacement units grants in period. Share-based payment award, options granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross Share-based payment award, options granted, exercise price per share Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price Award vesting period Share Based Compensation Arrangement By Share Based Payment Award Award Vesting Period1 Share-based payment award, options grant date fair value Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Grant Date Fair Value Number of shares awarded Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Replacement Units Grants In Period Share-based payment award, plan modification, incremental cost Share Based Compensation Arrangement By Share Based Payment Award Plan Modification Incremental Compensation Cost Share-based payment award, options, weighted-average grant date fair value Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value Risk-free interest rate Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Expected dividend yield Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate Expected term in years Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1 Expected volatility Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Outstanding. Stock Options, Beginning Balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number Options granted, Stock Options Options cancelled or forfeited, Stock Options Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period Options expired, Stock Options Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period Outstanding. Stock Options, Ending Balance Vested and expected to vest at September 30, 2022, Stock Options Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number Options exercisable at September 30, 2022, Stock Options Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Number Outstanding, Weighted Average Exercise Price, Beginning balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price Options granted, Weighted Average Exercise Price Options cancelled or forfeited, Weighted Average Exercise Price Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price Options expired, Weighted Average Exercise Price Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price Outstanding, Weighted Average Exercise Price, Ending balance Vested and expected to vest at September 30, 2022, Weighted Average Exercise Price Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Weighted Average Exercise Price Options exercisable at September 30, 2022, Weighted Average Exercise Price Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price Share based compensation arrangement By share based payment award options granted weighted average remaining contractual term1. Outstanding, Weighted Average Remaining Contractual Life Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2 Vested and expected to vest at September 30, 2022, Weighted Average Remaining Contractual Life Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1 Options exercisable at September 30, 2022, Weighted Average Remaining Contractual Life Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1 Share based compensation arrangement by share based payment award options grants in period intrinsic value. Share based compensation arrangement by share based payment award options cancelled or forfeited in period intrinsic value. Outstanding, Aggregate Intrinsic Value, Beginning Balance Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value Options granted, Aggregate Intrinsic Value Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Intrinsic Value Options cancelled or forfeited, Aggregate Intrinsic Value Share Based Compensation Arrangement By Share Based Payment Award Options Cancelled Or Forfeited In Period Intrinsic Value Outstanding, Aggregate Intrinsic Value, Ending Balance Vested and expected to vest at September 30, 2022, Aggregate Intrinsic Value Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value Options exercisable at Sepember 30, 2022, Aggregate Intrinsic Value Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1 Share-based payment award, options, compensation cost not yet recognized Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options Share-based payment award, compensation cost not yet recognized, weighted-average period of recognition Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1 Stock options were exercised during the period Stock Issued During Period Value Stock Options Exercised Share-based payment award, RSU/RSA granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Share-based payment award, vesting rights percentage Sharebased Compensation Arrangement By Sharebased Payment Award Award Vesting Rights Percentage Share-based payment award, unvested RSU/RSA granted, compensation cost not yet recognized Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Share Based Awards Other Than Options Nonvested, Number of Shares, Beginning Balance Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number Restricted units/stock granted, Number of Shares Vested, Number of Shares Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Cancelled or forfeited, Number of Shares Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period Nonvested, Number of Shares, Ending Balance Nonvested, Weighted Average Grant Date Fair Value per Share, Beginning Balance Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value Restricted units/stock granted, Weighted Average Grant Date Fair Value per Share Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value Vested, Weighted Average Grant Date Fair Value per Share Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value Cancelled or forfeited, Weighted Average Grant Date Fair Value per Share Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value Nonvested, Weighted Average Grant Date Fair Value per Share, Ending Balance Award requisite service vesting period Share Based Compensation Arrangement By Share Based Payment Award Award Requisite Service Period1 Share-based payment award, RSU/RSA granted, weighted average grant date fair value Percentage of common stock price purchased through payroll deductions Share Based Compensation Arrangement By Share Based Payment Award Maximum Employee Subscription Rate Percentage of payroll deductions of employee's compensation during offering period Share Based Compensation Arrangement By Share Based Payment Award Discount From Market Price Offering Date Maximum number of shares employees may purchase during offering period Share Based Compensation Arrangement By Share Based Payment Award Maximum Number Of Shares Per Employee Stock-based compensation expense Allocated Share Based Compensation Expense Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] General and Administrative Expense General And Administrative Expense [Member] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Stock-based compensation expense Net loss Net Income Loss Available To Common Stockholders Basic Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Securities Antidilutive Securities Excluded From Computation Of Earnings Per Share By Antidilutive Securities [Axis] Antidilutive Securities, Name Antidilutive Securities Name [Domain] Unvested RSUs Unvested RSAs Stock Options Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Anti-dilutive securities excluded from computation of diluted net loss per share Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Provision for income taxes Income Tax Expense Benefit Loss Contingencies [Table] Loss Contingencies [Table] Durham lease. Durham Lease Durham Lease [Member] Loss Contingencies [Line Items] Loss Contingencies [Line Items] Lease expense Operating Lease Expense Number of operating lease landlord square feet manufacturing facility Property Subject To Or Available For Operating Lease Number Of Units Operating lease commencement date Operations Commenced Date1 Operating lease term of contract Lessee Operating Lease Term Of Contract Operating lease extend term of contract Lessee Operating Lease Renewal Term Amount required to place in escrow account Escrow Deposit Operating leases initial direct costs. Operating leases initial direct costs Operating Leases Initial Direct Costs Build-to-suit asset. Built-to-suit lease liability. Equipment purchases and build-out of leased facility. Build-to-suit asset Build To Suit Asset Build-to-suit lease liability Built To Suit Lease Liability Equipment purchases and build-out of leased Facility Equipment Purchases And Build Out Of Leased Facility Schedule Of Restructuring And Related Costs [Table] Schedule Of Restructuring And Related Costs [Table] Restructuring Plan Restructuring Plan [Axis] Restructuring Plan Restructuring Plan [Domain] Exit and disposal activities. Exit and Disposal Activities Exit And Disposal Activities [Member] Restructuring Cost And Reserve [Line Items] Restructuring Cost And Reserve [Line Items] Percentage of headcount reduced Restructuring And Related Cost Number Of Positions Eliminated Period Percent Severance and termination-related costs Severance Costs1 Schedule Of Defined Benefit Plans Disclosures [Table] Schedule Of Defined Benefit Plans Disclosures [Table] Defined Benefit Plan Disclosure [Line Items] Defined Benefit Plan Disclosure [Line Items] Contribution to retirement savings plan Defined Contribution Plan Employer Discretionary Contribution Amount Upfront payment period. Subsequent Event [Table] Subsequent Event [Table] Underwritten public offering. Underwritten Public Offering Underwritten Public Offering [Member] Subsequent Event [Line Items] Subsequent Event [Line Items] Upfront payment period Upfront Payment Period Aggregate gross proceeds Proceeds From Issuance Of Private Placement Net proceeds after deducting underwriting discounts and commission